Endocrine Abstracts

Background: Higher body weight is associated with greater bone mineral density (BMD). Lean mass (LM) is positively related with bone parameters in adolescence. However, a number of controversial studies have suggested that fat mass (FM) has beneficial effect or has detrimental effect on BMD in adolescence. These contradictory results of FM on bone parameters might be developed by the non-linear relationship in the adolescent population.Objective: We eval...

Objectives: The aim of this study is to compare Friedewaldestimated and directly measured lowdensity lipoprotein cholesterol (LDLC) values and assess the concordance in guideline risk classification between the two methods.Methods: The data were derived from the 2009 to 2011 Korea National Health and Nutrition Survey (KNHANES). Analysis was done for 6454 subjects with lipid panels – total cholesterol (TC), directly measured LDL-C, high-density lipop...

Obesity is one of the leading causes of elevated cardiovascular disease (CVD) mortality and morbidity. Several indicators of abdominal obesity such as body mass index (BMI) and waist circumference (WC) are available. BMI and WC have limitations in stratifying cardio-metabolic risks. Another obesity measure, A Body Shape Index (ABSI), has been introduced but its applicability remains limited. To address this, the z-score of the log-transformed ABSI (LBSIZ) was recently develope...

Aim: An international expert committee, after considering data on association of HbA1c and retinopathy, recommended that diabetes be diagnosed when HbA1c is more than 48 mmol/mol (>6.5%), provided this assay is done in a standardized laboratory. However, the performance of HbA1c in detecting diabetes in the Korean population remains unknown. The purpose of this study was to evaluate the efficiency of HbA1c in diagnosing diabetes and to identify the optimal threshold in the...

Aim: HbA1c is recommended as a diagnostic criterion for diabetes in clinical practice guidelines for type 2 diabetes in 2011 (10). Although there have been several reports that compared HbA1c-based diagnosis for diabetes with glucose-based diagnosis in Koreans, it is thought that larger epidemiological studies are required to confirm the association of HbA1c and FPG for diagnosis of diabetes for the Korean population. We conducted this study to examine the relationship between...